Clinical features

Why?

Hypotension with chest pain makes a myocardial infarction more likely

Patient	Target Disorder and Reference Standard	Diagnostic Test	LR+ (95% CI)	Post-test Probability
attending emergency department with chest pain b (pre-test probability: 20%)	myocardial infarction (ECG and cardiac enzyme changes)	hypotension (systolic bp 80 mmHg or less)	3.1 (1.8 to 5.2)	44%

Hypertension on initial examination makes a distal aortic dissection slightly more likely but a proximal one less

Patient	Target Disorder and Reference Standard	Diagnostic Test	LR+ (95% CI)	Post-test Probability	LR- (95% CI)	Post-test Probability
suspected aortic dissection undergoing angiography c (pre-test probability: 1%)	distal aortic dissection (angiography, surgery or autopsy)	hypertension on initial examination (150/90 or more)	2.5 (1.5 to 3.6)	1.4%	0.47 (0.33 to 0.66)	0.47%
		hypertension on initial examination (150/90 or more)	0.19 (0.089 to 0.42)	0.19%	2.0 (1.6 to 2.5)	2.0%
		hypotension on initial examination (systolic < 100)	5.3 (2.0 to 14)	5.3%	0.82 (0.71 to 0.94)	0.82%