Therapy

Why?

• More patients are cured, particularly with leg ulcers and fewer require surgery. ^a
• Patients spend less time in hospital (on average 8 days fewer). ^a

Granulocyte colony stimulating factor speeds healing in extensive diabetic cellulitis

Patient a	Treatment	Comparison	Outcome	CER	RRR (95% CI)	NNT (95% CI)
diabetes and extensive cellulitis	granulocyte colony stimulating factor	placebo	surgery at at discharge	20%	100%	5 (3 to 40)
			persistent cellulitis at 7 days	80%	44% (4% to 67%)	3 (2 to 14)
			persistent ulcer	100%	20% (0% to 36%)	5 (3 to 40)