Clinical features

• a site of entry (e.g. leg ulcer, toe-web intertrigo, traumatic wound)
• lymphoedema, leg oedema or venous insufficiency
• obesity 

Why?

• These clinical features increase the risk of cellulitis developing.
• Diabetes, alcohol misuse and smoking are not significantly associated with an increased risk of cellulitis.

Lymphoedema and a site of entry increase the risk of cellulitis

Outcome	Risk Factor	PEER	OR (95% CI)	NNH (95% CI)
cellulitis  b	lymphoedema independent	0.1%	71.2 (5.6 to 908)	15 (2 to 220)
	site of entry independent		23.8 (10.7 to 52.5)	45 (20 to 100)
	leg oedema (excluding venous insufficiency) independent		2.5 (1.2 to 5.1)	670 (250 to 5000)
	venous insufficiency independent		2.9 (1.0 to 8.7)	530 (130 to infinity)
	overweight independent		2.0 (1.1 to 3.7)	1000 (370 to 10000)