Evidence-based On-call

Cardiac arrest

Immediate management

There is no clear benefit from amiodarone ^a

Why?

It increases survival to hospital admission in out-of-hospital cardiac arrest, but has no clear effect on survival to discharge ^a

Amiodarone increases survival to hospital admission following out-of-hospital cardiac arrest

Patient	Treatment	Comparison	Outcome	CER	RRR (95% CI)	NNT (95% CI)
out-of-hospital cardiac arrest ^a	amiodarone	placebo	survival to hospital admission at	35%	27% (2% to 59%)	11 (6 to 110)