Evidence-based On-call

Cardiac arrest

Immediate management

There is no clear benefit from vasopressin ^d

Why?

More patients are resuscitated than patients given epinephrine, but there is no clear effect on survival to discharge. ^a

Vasopressin increases successful resuscitation and survival at 24 hours

Patient	Treatment	Comparison	Outcome	CER	RRR (95% CI)	NNT (95% CI)
out-of-hospital cardiac arrest ^a	vasopressin	epinephrine	successful resuscitation	35%	100% (3.00% to 290%)	3 (2 to 17)
			survival at 24 hours	20%	200% (16% to 673%)	3 (1 to 8)