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Bradyarrhythmias

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Clinical features
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Therapy

 Sick sinus syndrome

Consider slow-release theophylline a  

Why?

  • It reduces overt heart failure a

Sick sinus syndrome: theophylline reduces the occurrence of overt heart failure

Patient Treatment Comparison Outcome CER RRR
(95% CI)		 NNT
(95% CI)
symptomatic sick sinus syndrome a theophylline no treatment overt heart failure
at 4 years 		17% 84%
(-28% to 98%) 		7
(4 to 130)


Expiry date: July 2003
Levels of Evidence used in grading these guides

Authors   E   Ashley , CM   Ball
Reviewer   B   McGovern
CAT Writers   E   Ashley , CM   Ball , CJ   Wotton