Therapy

DC cardioversion

Consider giving an infusion of ibutilide before cardioversion ^a  

Why?

• It increases the chance that patients will remain in sinus rhythm ^a

Pre-treatment with ibutilide helps maintain sinus rhythm following DC cardioversion

Patient	Treatment	Comparison	Outcome	CER	RRR (95% CI)	NNT (95% CI)
acute AF a	ibutilide before cardioversion	placebo before cardioversion	sinus rhythm at 12 months	72%	-39% (-65% to -17%)	4 (2 to 6)