Therapy

• amiodarone iv ^a   or oral  ^a  

Why?

• Amiodarone is more effective at cardioversion than digoxin ^a or verapamil ^a though not clearly better than propafenone ^d

Amiodarone is more effective at cardioversion than digoxin or verapamil

Patient	Treatment	Comparison	Outcome	CER	RRR (95% CI)	NNT (95% CI)
acute AF a	amiodarone	digoxin	sinus rhythm at 24 hours	71%	-30% (-72% to 1%)	5 (2 to 170)
paroxysmal AF a	amiodarone	verapamil	sinus rhythm at 3 hours	0%		1 (1 to 2)