Therapy

• procainamide ^a  

Why?

• Procainamide is more effective at cardioversion than propafenone ^a or digoxin ^a

Procainamide is more effective at cardioversion than propafenone or digoxin

Patient	Treatment	Comparison	Outcome	CER	RRR (95% CI)	NNT (95% CI)
acute or chronic AF a	procainamide	propafenone	sinus rhythm at 48 hours	47%	36% (5% to 56%)	4 (2 to 19)
acute fast AF a	procainamide and digoxin	digoxin	sinus rhythm at 60 minutes	28%	81% (11% to 195%)	4 (2 to 19)