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Asthma exacerbation

Prevalence
Clinical features
Differential Diagnosis
Investigations
Therapy
Prevention
Prognosis
Prevention

There is no clear benefit from recommending influenza vaccination. d

Why?

  • Influenza vaccination does not clearly prevent exacerbations in the long-term, but may trigger one in the short-term. a
Patient Treatment Comparison Outcome CER RRR
(95% CI)
NNT
(95% CI)
asthma a influenza split virus or surface antigen vaccine  placebo asthma exacerbation
at 4 days
4.2% 73%
(3% to 92%)
33
(17 to 330)

 

Expiry date: November 2003
Levels of Evidence used in grading these guides

Authors   B   Wong , CM   Ball
Reviewer   B R   O'Driscoll
CAT Writers   B   Wong , CM   Ball