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Asthma exacerbation

Prevalence
Clinical features
Differential Diagnosis
Investigations
Therapy
Prevention
Prognosis
Clinical features

Ask about current medication and its use b  

Why?

  • Patients who have started 3 or more new types of medication in the last year are at increased risk of dying b
  • Irregular or infrequent use increases the risk of dying b

Poor compliance and multiple medications started in the last year are associated with asthma death

Outcome b Risk Factor PEER OR
(95% CI)
NNH
(95% CI)
death from asthma  ≥ 3 categories of asthma drug prescribed in last year
independent
0.0057% 3.0
(1.04 to 10.5)
8800
(1900 to 440000)
death from asthma  non-compliance with treatment
independent
0.0057% infinity
(5.2 to infinity)
infinity
(4200 to infinity)

 

Expiry date: November 2003
Levels of Evidence used in grading these guides

Authors   B   Wong , CM   Ball
Reviewer   B R   O'Driscoll
CAT Writers   B   Wong , CM   Ball