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Aortic dissection

Prevalence
Clinical features
Differential diagnosis
Investigations
Therapy
Prevention
Prognosis
Therapy

Give analgesia d e.g. diamorphine 5mg iv ( in small or elderly patients 2.5 mg)

Discuss with cardiothoracic surgeon (and cardiologist) and organise transfer to a cardiothoracic unit or intensive care unit d

Meanwhile give antihypertensive therapy d . Options include d:

  • labetalol iv
  • nitroprusside and propranolol iv
  • trimetaphan iv
Consider inserting 
  • an intra-arterial line for constant bp monitoring if using nitroprusside or trimetaphan  d
  • a urinary catheter  d

Aim  for systolic blood pressure of 100-120 mmHg provided the urine output >30 ml/ hour  d


Consider surgery a for patients with d
  • acute dissection of ascending aorta
  • acute dissection of descending aorta with
    • signs of impending rupture (persisting pain, hypotension, left-sided haemothorax )
    • Marfan syndrome
  • chronic dissection, if aorta > 5-6 cm in diameter or symptoms

Consider medical therapy (long-term antihypertensive therapy) for patients with
  • acute or chronic dissection of descending aorta d  
 

Expiry date: August 2004
Levels of Evidence used in grading these guides

Author   CM   Ball
Reviewer   M   Briggs
CAT Writers   CM   Ball , CJ   Wotton