Indications

Score one point for each of the following risk factors ^a  

• aged 65 or more 
• history of stroke 
• history of gastrointestinal bleed 
• recent myocardial infarction, Hct < 30%, Cr > 133 µmol/l or diabetes mellitus 

Risk of major bleeding on anticoagulation therapy

Why?

• This bleeding index helps predict outpatients at high risk for major bleeding when anticoagulated ^a

Half of patients classified at high risk have a major bleed within 4 years

risk a	% with major bleeding at 48 months (95% CI)	NNF  (95% CI)
high	53%  (11% to 97%)	2  (1 to 9)
medium	12%  (5% to 19%)	8  (5 to 20)
low	3%  (0% to 8%)	40  (13 to infinity)