Therapy

• heparin ^d 

Why?

• Heparin is more effective than aspirin at reducing MI ^a , but not clearly less effective than LMWH ^a  

• Adding heparin to aspirin probably reduces subsequent MI or recurrent angina, but has no clear effect on bleeding or need for revascularisation. ^d 

Heparin prevents more MI than aspirin

Patient	Treatment	Comparison	Outcome	CER	RRR (95% CI)	NNT (95% CI)
unstable angina or non-Q wave MI a	heparin	aspirin	MI at 6 days	3.8%	77% (-3% to 95%)	35 (18 to 440)