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Acute coronary syndrome

Prevalence
Clinical features
Differential diagnosis
Investigations
Therapy
Prevention
Prognosis
Therapy

Coronary artery bypass graft surgery

Consider giving acadesine perioperatively. a  

Why?

  • It reduces perioperative myocardial infarction and cardiac death. a

Acadesine reduces perioperative MI and death

Patient a Treatment Comparison Outcome CER OR
(95% CI)
NNT
(95% CI)
CABG   acadesine placebo perioperative MI
at 4 days
4.9% 0.69
(0.51 to 0.95)
68
(43 to 430)
      cardiac death
at 4 days
1.3% 0.52
(0.27 to 0.98)
120
(78 to 2900)

 

Expiry date: June 2003
Levels of Evidence used in grading these guides

Authors   CM   Ball , N   Shenker
Reviewer   I K   Jang
CAT Writers   N   Shenker , CJ   Wotton , CM   Ball , RS   Phillips