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Acute coronary syndrome

Prevalence
Clinical features
Differential diagnosis
Investigations
Therapy
Prevention
Prognosis
Therapy

Angioplasty

Insert a stent in new a and chronic occlusions a  

Why?

  • Stent insertion reduces restenosis a and recurrent ischaemia, a but increases the risk of bleeding or vascular complications. a
  • Patients spend on average 5 days longer in hospital. a
  • Fewer patients require repeat angiography. a

Stent insertion reduces restenosis, recurrent ischaemia , but increases the risk of complications

Patient Treatment Comparison Outcome CER RRR
(95% CI)
NNT
(95% CI)
stable angina and a single new lesion a stent insertion no stent repeat angiography
at 12 months
21% 51%
(25% to 69%)
9
(6 to 23)
stable angina and new proximal left artery descending coronary artery lesion a stent insertion no stent restenosis
at 12 months
40% 54%
(15% to 75%)
5
(3 to 17)
      death, MI or recurrence of angina
at 12 months
30% 56%
(6% to 79%)
6
(3 to 45)
angina with chronic coronary artery occlusion stent insertion no stent restenosis
at 9 months
69% 53%
(29% to 69%)
3
(2 to 5)
      recurrent ischaemia
at 9 months
46% 69%
(38% to 85%)
3
(2 to 6)
angina with chronic coronary artery occlusion a stent insertion no stent bleeding and vascular complications
at 9 months
0.0% -%
-14
(-250 to -7)

 

Expiry date: June 2003
Levels of Evidence used in grading these guides

Authors   CM   Ball , N   Shenker
Reviewer   I K   Jang
CAT Writers   N   Shenker , CJ   Wotton , CM   Ball , RS   Phillips