Therapy

Offer angioplasty ^a to patients with single vessel disease. ^b  

Why?

• Patients with non-acute coronary artery disease who have angioplasty compared with medical therapy have less angina  ^a and require less medication. ^a  
• There is no clear effect on death or myocardial infarction. ^a
• Patients who have angioplasty are more likely to require a CABG, but not clearly more likely to require further angioplasty. ^a

Angioplasty reduces angina but increases the risk of CABG compared with medical therapy

Patient a	Treatment	Comparison	Outcome	CER	OR (95% CI)	NNT (95% CI)
non-acute coronary artery disease	angioplasty	medical therapy	angina at 3 years	71%	0.70 (0.50 to 0.98)	13 (6 to 240)
	angioplasty	medical therapy	CABG at 3 years	4.1%	1.59 (1.09 to 2.32)	-44 (-280 to -20)

Angioplasty reduces need for antianginal medication compared with medical therapy

Patient a	Treatment	Comparison	Outcome	CER	RRR (95% CI)	NNT (95% CI)
coronary artery disease with >50% stenosis in at least 1 vessel	angioplasty +/- stent	medical therapy	on 1 or fewer anti-anginal drugs at 3 years	47%	-60% (-90% to -35%)	4 (3 to 5)