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Acute coronary syndrome

Prevalence
Clinical features
Differential diagnosis
Investigations
Therapy
Prevention
Prognosis
Therapy

For patients with severe refractory unstable angina, consider adding nicorandil. a  

Why?

  • Nicorandil reduces chest pain in patients with refractory unstable angina on aspirin, beta-blockers and diltiazem. a
  • There is no clear effect on subsequent MI or death. d

Nicorandil reduces recurrent chest pain in refractory unstable angina

Patient Treatment Comparison Outcome CER RRR
(95% CI)		 NNT
(95% CI)
unstable angina on aspirin, beta-blockers and diltiazem a nicorandil placebo recurrent chest pain
at 2 days 		36% 43%
(9% to 64%) 		6
(4 to 29)

 

Expiry date: June 2003
Levels of Evidence used in grading these guides

Authors   CM   Ball , N   Shenker
Reviewer   I K   Jang
CAT Writers   N   Shenker , CJ   Wotton , CM   Ball , RS   Phillips