Browse Guides  internal medicine  cardiology

Acute coronary syndrome

Prevalence
Clinical features
Differential diagnosis
Investigations
Therapy
Prevention
Prognosis
Prevention

Consider giving patients vitamin E supplements (alpha-tocopherol) a  

Why?

  • Alpha-tocopherol reduces non-fatal myocardial infarction a . There is no clear effect on mortality or stroke. a

Vitamin E reduces non-fatal MI in proven coronary artery disease

Patient Treatment Comparison Outcome CER RRR
(95% CI)		 NNT
(95% CI)
 proven coronary artery disease a alpha-tocopherol placebo non-fatal myocardial infarction
at 1.4 years 		4.2% 68%
(42% to 82%) 		35
(23 to 70)

 

Expiry date: June 2003
Levels of Evidence used in grading these guides

Authors   CM   Ball , N   Shenker
Reviewer   I K   Jang
CAT Writers   N   Shenker , CJ   Wotton , CM   Ball , RS   Phillips