Prevention

using gemfibrozil for patients with a low HDL levels ^a

Why?

• Men with low HDL levels who take gemfibrozil are less likely to have an MI or die from heart disease.  There is no clear effect on stroke ^a

Gemfibrozil reduces MI and death from heart disease in patients with low HDL levels

Patient	Treatment	Comparison	Outcome	CER	RRR (95% CI)	NNT (95% CI)
MI or angina, and HDL <1.0 mmol/l a	gemfibrozil	placebo	non-fatal MI or death due to heart disease at 5 years	22%	20% (6.0% to 32%)	23  (12 to 77)