Prevention

Alternatives include clonidine ^a - but adverse effects are common ^c

Why?

• Clonidine helps smokers quit. ^a  
• However adverse effects - usually dry mouth, sedation and dizziness - occur in 23% to 92% ^c

Clonidine helps smokers quit

Patient	Treatment	Comparison	Outcome	CER	OR (95% CI)	NNT (95% CI)
smoker a	clonidine	placebo	stopped smoking at 3 months	14%	1.89 (1.30 to 2.74)	10 (6 to 28)