Prevention

Offer buproprion ^a

Why?

• Buproprion helps smokers quit and is more effective than nicotine patches. ^a
• Combining nicotine patches and buproprion is not clearly more effective than buproprion alone. ^d

Buproprion is more effective than nicotine patches at helping smokers quit

Patient	Treatment	Comparison	Outcome	CER	OR (95% CI)	NNT (95% CI)
smoker a	buproprion	placebo	sustained smoking cessation at 12 months	7.9%	2.73 (1.90 to 3.94	9 (6 to 16)
	buproprion	nicotine patch	sustained smoking cessation at 12 months	9.8%	2.03 (1.22 to 3.37)	8 (5 to 21)