Prevention

Why?

• Patients with coronary artery disease who have cholesterol-lowering therapy are less likely to die, particularly from heart disease. ^a

Lowering cholesterol reduces mortality

Patient	Treatment	Comparison	Outcome	CER	RRR (95% CI)	NNT (95% CI)
coronary artery disease a	cholesterol-lowering therapy	no therapy	death at 2 years	10%	16% (12% to 19%)	63 (51 to 81)
			death from coronary heart disease at 2 years	6.4%	28% (24% to 32%)	56 (48 to 67)

• Patients with cholesterol levels < 6.2 mmol/l who take pravastatin are less likely to have another myocardial infarction or die from heart disease, or require invasive therapy. ^a
• Cholesterol-lowering therapy does not clearly increase violent death or suicide. ^d