Browse Guides  internal medicine  cardiology

Acute coronary syndrome

Prevalence
Clinical features
Differential diagnosis
Investigations
Therapy
Prevention
Prognosis
Prevention

Arrange for your patient to attend a structured secondary prevention programme. a

Cholesterol

Lower cholesterol levels a even for patients with average levels (cholesterol 4.0 mmol/l to 6.2 mmol/l) a using 

  • diet modification: a encourage patients to eat less fat a (particularly cholesterol) a  and more oats a, fish a and soy protein. b
  • a statin a, particularly to patients revascularised following post-infarct angina. a  
  • gemfibrozil for patients with low HDL levels a
  • garlic a

There is no clear benefit from referring your patient to a dietician - self-help material is equally effective. a  

Diet

Consider giving patients vitamin E supplements (alpha-tocopherol) a

Hypertension

Treat hypertension a

Smoking

Encourage patients to stop smoking a, and ask nurses a and other staff  a to provide further advice.

Offer buproprion a

Alternatives include

  • nicotine replacement therapy - a combination works best (e.g. patches a and gum a
  • nortryptiline a
  • clonidine - but adverse effects are common a 

Arrange for self-help material and follow-up advice after discharge, with personalised feedback. a

Alternatives include

  • individual counselling a 
  • telephone-based counselling b 
There is no clear benefit from 
  • a exercise programme.   a 
  • anxiolytics    a 
  • silver acetate  d

Exercise

Offer an exercise rehabilitation programme. a

There is no clear benefit from giving postmenopausal women oestrogen and progestin d

Expiry date: June 2003
Levels of Evidence used in grading these guides

Authors   CM   Ball , N   Shenker
Reviewer   I K   Jang
CAT Writers   N   Shenker , CJ   Wotton , CM   Ball , RS   Phillips