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Acute coronary syndrome

Prevalence
Clinical features
Differential diagnosis
Investigations
Therapy
Prevention
Prognosis
Clinical features

Use the following clinical prediction rule to help determine admission to coronary care units. a   
Look for the following risk factors:
  • pain worse than prior angina or the same as the pain associated with a prior myocardial infarction
  • systolic blood pressure <110 mmHg
  • crackles above the bases bilaterally
  • ST elevation or Q waves, not known to be old, in two or more leads
  • ST segment or T wave changes, not known to be old, indicative of myocardial ischaemia

Risk of major complications

Group a risk of major complication at 4 days
suspected MI on ECG or suspected ischaemia on ECG and 2 or more risk factors high
suspected ischaemia on ECG and 1 or no risk factor moderate
one risk factor with no MI or ischaemia on ECG low
no risk factors very low
 

Why?

A clinical prediction rule can help identify patients at risk of having major complications

Risk of major complication at 4 days %
(95% CI)
NNF
(95% CI)
suspected MI on ECG or suspected ischaemia ECG and 2 or more risk factors a 16%
(12% to 20%)
6
(5 to 8)
suspected ischaemia on ECG and 1 or no risk factor  7.8%
(6.0% to 9.6%)
13
(11 to 17)
one risk factor with no MI or ischaemia  3.9%
(2.7% to 5.2%)
26
(19 to 37)
no risk factors  0.58%
(0.29% to 0.87%)
170
(110 to 340)

 

Expiry date: June 2003
Levels of Evidence used in grading these guides

Authors   CM   Ball , N   Shenker
Reviewer   I K   Jang
CAT Writers   N   Shenker , CJ   Wotton , CM   Ball , RS   Phillips