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Anaphylaxis

Prevalence
Causes
Clinical features
Differential diagnosis
Investigations
Therapy
Prevention
Prognosis
Clinical features

Ask about a history of asthma or atopy c  

Why?

Asthma or beta-blocker use is associated with anaphylaxis

Outcome  Risk Factor PEER OR
(95% CI)		 NNH
(95% CI)
anaphylactoid reaction to contrast media  c history of asthma or atopy
not independent 		0.17%  4.54
(1.03 to 20.1)		 170
(32 to 20000)
  beta-blocker use or asthma
not independent 		0.17% 3.43
(1.5 to 8.2)		 250
842 to 1300)
 

Expiry date: September 2004
Levels of Evidence used in grading these guides

Authors   M   Bennett , RS   Phillips
Reviewer   M   Daniel
CAT Writers   CM   Ball , M   Bennett, DM Lang