Clinical features

• recent onset pallor ^c  
• weight loss (> 7 kg in 6 months) ^c  

Why?

Recent pallor and weight loss make anaemia slightly more likely

Patient	Target Disorder and Reference Standard	Diagnostic Test	LR+ (95% CI)	Post-test Probability	LR- (95% CI)	Post-test Probability
suspected anaemia c (pre-test probability: 19%)	anaemia (haemoglobin < 8.0 g/dl)	recent pallor	2.3 (1.7 to 3.1)	35%	0.21 (0.11 to 0.42)	5%
		weight loss (> 7 kg in 6 months)	1.5 (1.0 to 2.2)	26%	0.71 (0.52 to 0.99)	14%