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Deep vein thrombosis

Prevalence
Clinical features
Differential diagnosis
Investigations
Therapy
Prevention
Prognosis
Prevention

All patients who are  a  
  • having major surgery (especially orthopaedic) a  
  • likely to have poor mobility a  
    • major trauma a  
    • leg plaster cast a  
    • spinal cord injury a  
    • stroke a  
    • decompensated heart failure a  
    • myocardial infarction or unstable angina a  
  • at increased risk for DVT
    • old a  
    • active cancer having chemotherapy a  
    • recurrent venous thromboembolism a  
    • pregnant with thrombophilia c 
should have venous thromboembolism prophylaxis. a  
  • using  thigh-length graduated compression stockings a 
  • with a the following if required - 

Moderate-risk cases   
  • low-dose heparin a  5000 units every 12 hours (adjusted so aPTT 1.0 to 1.1) a  

High-risk cases (major abdominal, gynaecological , neurosurgical, cardiovascular or orthopaedic surgery) 
  • Any of 
    • low molecular weight heparin a e.g. 40 mg enoxaparin daily. a  
    • thigh-length intermittent pneumatic compression a  
    • Alternatives include
      • warfarin a  
      • hirudin a  
      • anti-platelet drugs a  (aspirin, dipyridamole, hydroxychloroquine, ticlodopine)
Continue prophylaxis for 4 to 6 weeks. a  

 

Expiry date: January 2004
Levels of Evidence used in grading these guides

Author   C   Ball
Reviewer   J   Ginsberg
CAT Writers   C   Ball , B   Phillips