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Deep vein thrombosis

Prevalence
Clinical features
Differential diagnosis
Investigations
Therapy
Prevention
Prognosis
Investigations

High risk for DVT 
  • Positive scan: DVT
  • Negative scan: Venous thromboembolism remains so likely that a venogram is needed.
    • If the venogram is positive: DVT
    • If the venogram is negative: no DVT
Moderate risk for DVT
  • Positive scan: DVT
  • Negative scan: Repeat the scan in one week and withhold anticoagulation.
    • If it is positive: DVT
    • If it is negative: no DVT
Low risk for DVT
  • Positive scan: Venous thromboembolism remains so unlikely that a venogram is needed.
    • If the venogram is positive: DVT
    • If the venogram is negative: no DVT
  • Negative scan: no DVT
Why?

An ultrasound scan can help diagnose and exclude a DVT

Patient Target Disorder and
Reference Standard
Diagnostic Test LR+
(95% CI)
Post-test Probability LR-
(95% CI)
Post-test Probability
suspected DVT a
(pre-test probability: 16%)
deep vein thrombosis
(venogram)
ultrasound 22
(18 to 28)
81% 0.10
(0.09 to 0.12)
2%
clinical high risk for a DVT a
(pre-test probability: 75%)
    infinity
100% 0.09
21%
clinical moderate risk for a DVT a
(pre-test probability: 17%)
    53
92% 0.39
7%
clinical low risk for a DVT a
(pre-test probability: 3%)
    24
43% 0.34
1%
 

 

Expiry date: January 2004
Levels of Evidence used in grading these guides

Author   C   Ball
Reviewer   J   Ginsberg
CAT Writers   C   Ball , B   Phillips