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Exacerbation of Chronic Obstructive Pulmonary Disease

Prevalence
Clinical features
Differential Diagnosis
Investigations
Therapy
Prevention
Prognosis
Clinical features

Look for a prolonged expiratory time a  

Note:

  • Measure expiratory time, by timing expiratory sounds that are audible over the sternum during forced expiration. 
Why?

A prolonged expiratory time makes COPD more likely

Patient Target Disorder and
Reference Standard
Diagnostic Test LR+
(95% CI)
Post-test Probability
suspected COPD a
(pre-test probability: 9%)
COPD
(spirometry)
forced expiratory time > 9 sec 4.8
32%
    6-9 sec 2.7
21%
    <6 sec 0.45
4%

 

Expiry date: July 2003
Levels of Evidence used in grading these guides

Author   CM   Ball
Reviewer   N R   Anthonisen
CAT Writers   B   Phillips , CJ   Wotton , CM   Ball