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Exacerbation of Chronic Obstructive Pulmonary Disease

Prevalence
Clinical features
Differential Diagnosis
Investigations
Therapy
Prevention
Prognosis
Clinical features

Look for a  
  • a barrel chest
  • subxyphoid cardiac apical pulse
  • decreased cardiac dullness on percussion
  • decreased breath sounds
  • wheezing
  • crackles
  • hyperresonance 

Why?

Wheezing, a barrel chest and decreased cardiac dullness make COPD more likely

Patient Target Disorder and
Reference Standard
Diagnostic Test LR+
(95% CI)
Post-test Probability LR-
(95% CI)
Post-test Probability
suspected COPD a
(pre-test probability: 9%)
COPD
(spirometry)
wheezing on examination 12
(1.7 to 98)
54% 0.87
(0.79 to 0.96)
8%
suspected COPD a
(pre-test probability: 9%)
COPD
(spirometry)
barrel chest 10
50% 0.90
8%
    decreased cardiac dullness 10
50% 0.88
8%
    crackles 5.9
37% 0.95
9%
    hyperresonance 4.8
32% 0.73
7%
    subxyphoid cardiac apical impulse 4.6
31% 0.94
7%
    decreased breath sounds 3.7
27% 0.70
9%

 

Expiry date: July 2003
Levels of Evidence used in grading these guides

Author   CM   Ball
Reviewer   N R   Anthonisen
CAT Writers   B   Phillips , CJ   Wotton , CM   Ball