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Diagnosis Economics Harm/ aetiology Prognosis Therapy Rehabilitation Other therapies

Stroke lowering blood pressure acutely does not clearly reduce death or disability and can be harmful Level of evidence 1a Expiry Date November 2003 Stroke no clear role for mannitol given acutely Level of evidence 1a- Expiry Date November 2003 Stroke heparinoids and LMWH lead to fewer DVT than unfractionated heparin but are not clearly safe. Level of evidence 1a- Expiry Date November 2003 Stroke higher doses of LMWH were not clearly better than lower ones. Level of evidence 1b- Expiry Date November 2003 Stroke no benefit from calcium-channel blockers Level of evidence 1a Expiry Date November 2003 Stroke gavestinel, a glycine antagonist, did not reduce mortality or disability Level of evidence 1b Expiry Date November 2003 Stroke no clear role for glycerol Level of evidence 1a- Expiry Date November 2003 Stroke acute interventions to alter blood pressure had no clear effect on death. Level of evidence 1a- Expiry Date December 2002 Stroke theophylline has no effect on death. Level of evidence 1a- Expiry Date December 2002 Stroke haemodilution has no clear effect on death. Level of evidence 1a- Expiry Date December 2002 Stroke routine anticoagulant therapy has no effect on death, dependence or recurrent stroke Level of evidence 1a Expiry Date November 2002 Stroke no clear benefit from anticoagulation if there is no embolic source Level of evidence 1a Expiry Date November 2002 Stroke corticosteroids had no clear effect on death. Level of evidence 1a- Expiry Date December 2002 Stroke prostacyclin had no clear effect on death. Level of evidence 1a- Expiry Date December 2002 Stroke haematoma evacuation has no clear effect on mortality in intracerebral haemorrhage Level of evidence 1b- Expiry Date June 2003 Stroke gangliosides have no clear effect on death. Level of evidence 1a- Expiry Date December 2002 Stroke surgery had no clear effect on death or dependency in haemorrhage Level of evidence 1a- Expiry Date December 2002 Stroke immediate anticoagulation had no clear effect on recurrent embolic stroke. Level of evidence 1b- Expiry Date June 2003 Stroke pentoxifylline, propentofylline and pentifylline had no clear effect on death. Level of evidence 1a- Expiry Date December 2002 Stroke piracetam had no clear effect on death or dependency. Level of evidence 1a- Expiry Date June 2003 Stroke glycerol may decrease early death. Level of evidence 1a Expiry Date December 2002 Stroke fibrinogen depleting agents had no clear effect on death or disability. Level of evidence 1a- Expiry Date December 2002