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Economics Prognosis Therapy Bleeding Heparin LMWH Warfarin

Anticoagulation more strokes and bleeds occurred when INR was 5.0 or more. Level of evidence 2b Expiry Date June 2003 Anticoagulation increased bleeding with supratherapeutic INR and high therapeutic ranges. Level of evidence 2b Expiry Date June 2003 Anticoagulation patients over 72 years old were at increased risk of bleeding on heparin. Level of evidence 1b Expiry Date June 2003 Anticoagulation no clear evidence for increased risk of recurrent venous thromboembolism with sub therapeutic aPTT levels. Level of evidence 1a Expiry Date June 2003 Anticoagulation paracetamol caused supratherapeutic INR levels in patients on warfarin. Level of evidence 3b Expiry Date June 2002 Anticoagulation bleeding occurred more often in patients with comorbid disease and commonly from the GI tract. Level of evidence 2a Expiry Date June 2002 Anticoagulation bleeding is more likely with more co-morbid conditions and supratherapeutic levels. Level of evidence 1a Expiry Date June 2002 Anticoagulation a tenth had a major bleed with long-term warfarin. Level of evidence 1b Expiry Date December 2001 Anticoagulation a clinical prediction rule can identify patients at increased risk of major bleeding Level of evidence 1a Expiry Date October 2001 Anticoagulation and DVT subtherapeutic aPTT after heparin increased risk of DVT. Level of evidence 2b Expiry Date June 2002 Anticoagulation and bleeding increased risk if INR >4.5 or started in the last three months. Level of evidence 1b Expiry Date June 2002 Anticoagulation and intracranial haemorrhage increased risk with INR >4.0, previous stroke or artificial heart valves. Level of evidence 3b Expiry Date June 2002 Anticoagulation and mechanical heart valves fewest strokes and bleeds occurred when INR is 2.5-4.9. Level of evidence 4 Expiry Date June 2002 Heparin and pre-menopausal women increased risk of osteopenia with prolonged use. Level of evidence 4 Expiry Date June 2002 Pregnancy and heparin low-risk of vertebral fractures and bleeds Level of evidence 4 Expiry Date June 2002 Pregnancy and heparin prolonged use led to a small reduction in femur bone density. Level of evidence 4 Expiry Date June 2002 Venous thromboembolism fatal PEs are rare. Level of evidence 1a Expiry Date May 2003 Warfarin therapy INR took between 5 and 8 days after discontinuation to reach 1.2. Level of evidence 2b Expiry Date June 2003