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Diagnosis Economics Prognosis Therapy Angioplasty Anticoagulation Bypass surgery Secondary prevention

Angina ß-blockers, nitrates and calcium antagonists are not clearly different. Level of evidence 1a- Expiry Date March 2003 Coronary artery disease alpha-tocopherol reduced non-fatal myocardial infarction. Level of evidence 1b Expiry Date March 2003 Coronary heart disease verapamil decreases nonfatal reinfarction in cardiovascular disease. Level of evidence 1a Expiry Date March 2003 Ischaemic heart disease no clear benefit from treating ECG changes rather than symptoms. Level of evidence 1b- Expiry Date March 2003 Ischaemic heart disease increased mortality with short acting nifedipine. Level of evidence 2a Expiry Date July 2003 Ischaemic heart disease calcium channel blockers did not increase cancer. Level of evidence 1b Expiry Date June 2003 Unstable angina intravenous nitrates reduced angina attacks. Level of evidence 1b Expiry Date July 2003 Unstable angina diltiazem was probably as good as propranolol in reducing angina attacks. Level of evidence 1b- Expiry Date June 2003 Unstable angina refractory: n-acetylcysteine reduced MI, but caused more symptomatic hypotension. Level of evidence 2b Expiry Date July 2003 Unstable angina refractory: thoracic epidural anaesthesia reduced episodes of angina and ischaemia. Level of evidence 1b Expiry Date June 2003 Unstable angina diltiazem reduced chest pain. Level of evidence 1b- Expiry Date July 2003 Unstable angina intravenous diltiazem was more effective than iv nitrate. Level of evidence 1b Expiry Date July 2003 Unstable angina chest pain observation units had no clear benefit. Level of evidence 1b- Expiry Date March 2003 Unstable angina nifedipine with propranolol and long-acting nitrates reduced death, MI and surgery. Level of evidence 1b Expiry Date June 2003 Unstable angina nifedipine should not be used alone. Level of evidence 1b Expiry Date June 2003 Unstable angina topical nitroglycerin and oral N-acetylcysteine reduced revascularisation interventions, but cause severe headaches. Level of evidence 1b Expiry Date July 2003 Unstable angina buccal nitroglycerin caused fewer headaches than intravenous. Level of evidence 1b Expiry Date July 2003 Unstable angina nicorandil reduced chest pain in patients on maximal therapy. Level of evidence 1b Expiry Date June 2003 Unstable angina adding a beta-blocker to standard medical therapy and calcium blocker shortened length and recurrence of angina. Level of evidence 1b Expiry Date July 2003 Unstable angina or MI role of calcium-channel blockers is unclear. Level of evidence 1a Expiry Date March 2003