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Diagnosis Economics Prognosis Therapy Angioplasty Anticoagulation Bypass surgery Secondary prevention

Antiplatelet therapy reduces deaths, strokes, MI. Level of evidence 1a Expiry Date July 2004 Coronary heart disease eptifibatide decreased death or nonfatal MI. Level of evidence 1b Expiry Date March 2003 Unstable angina tirofiban was more effective than heparin at preventing cardiac events. Level of evidence 1b Expiry Date June 2003 Unstable angina heparin prevented more myocardial infarctions than aspirin. Level of evidence 1b Expiry Date July 2003 Unstable angina dalteparin was probably as effective as unfractionated heparin. Level of evidence 1b- Expiry Date July 2003 Unstable angina abciximab had no clear effect on long-term mortality. Level of evidence 1b- Expiry Date March 2003 Unstable angina heparin and aspirin may be better than aspirin alone. Level of evidence 1a- Expiry Date July 2003 Unstable angina LMWH reduced death and MI compared with placebo. Level of evidence 1b Expiry Date July 2003 Unstable angina stopping heparin without aspirin caused recurrent angina and increased urgent interventions. Level of evidence 1b Expiry Date July 2003 Unstable angina tirofiban has no clear effect on long-term mortality. Level of evidence 1b Expiry Date March 2003 Unstable angina ticlopidine decreased nonfatal MI but not cardiovascular mortality. Level of evidence 1b Expiry Date March 2003 Unstable angina enoxaparin was not clearly better than unfractionated heparin. Level of evidence 1b- Expiry Date March 2003 Unstable angina hirudin decreased cardiovascular death, MI or refractory angina. Level of evidence 1b Expiry Date March 2003 Unstable angina moderate intensity warfarin decreases rehospitalisation with unstable angina. Level of evidence 1b Expiry Date March 2003 Unstable angina nicorandil reduced chest pain in patients on maximal therapy. Level of evidence 1b Expiry Date June 2003 Unstable angina enoxaparin reduced cardiac outcomes Level of evidence 1b Expiry Date March 2003 Unstable angina refractory: a glycoprotein IIb/IIIa inhibitor reduced death, MI and urgent revascularisation. Level of evidence 1b Expiry Date July 2003 Unstable angina or MI hirudin prevented more infarcts but caused more bleeding. Level of evidence 1b Expiry Date July 2003 Unstable angina, non-Q wave MI aspirin reduced deaths and non-fatal myocardial infarctions. Level of evidence 1b Expiry Date June 2003