Stroke: haemorrhage was common in young patients

Clinical bottom line (level 2c)

  1. One in nine young patients with a first stroke died within 30 days.
  2. Subarachnoid haemorrhage and intracerebral haemorrhage were common in young patients.
Marini et al: Stroke 2001; 32 : 52-56
Expires November 2003

The study

Prospective cohort study with objective outcomes, not adjusted for confounding factors, not validated in an independent set of patients.

Setting: district, Italy

89 patients (aged mean 36, 62% male) with a first-ever stroke

Excluded if
  • perinatal intracerebral haemorrhage
  • transient ischaemic attack or recurrent stroke
  • stroke due to trauma
  • residence outside district
  • aged 45 or more



100% followed for 30 days
Outcomes studied:
  • subarachnoid haemorrhage
  • intracerebral haemorrhage
  • cerebral infarction
  • death at 30 days

    The evidence

    outcome time to outcome number of patients/total number %
    (95% CI)
    subarachnoid haemorrhage 30 days 20/89 22%
    (14% to 31%)
    intracerebral haemorrhage 30 days 18/89 20%
    (12% to 29%)
    cerebral infarction 30 days 51/89 57%
    (47% to 68%)
    death at 30 days 30 days 10/89 11%
    (4.7% to 18%)

    Comments

    1. Longer follow-up indicated that patients with a subarachnoid haemorrhage made the best functional recovery and patients with a cerebral infarction the worst.

    Citation

    1. Marini C, Totaro R, De Santis F, et al: stroke in young adults in the community-based L'Aquila Registry: incidence and prognosis. Stroke 2001; 32 : 52-56
    Search Terms: from ACP Journal Club other articles noted
    Contributor: Chris Ball, November 2001
    Reviewer:

    Clinical Question.
    Patient young patient
    Intervention or Exposure first stroke
    Outcome death
    		•