Cardiac arrest: pneumatic trousers had no clear effect.

Clinical bottom line (level 1b-)

  1. Patients in refractory cardiac arrest who were treated with pneumatic trousers, had no clear difference in survival than those not given pneumatic trousers.
  2. Patients who were given pneumatic trousers had no clear difference in resuscitation than those not given pneumatic trousers.
Mahoney and Mirick: Annals of Emergency Medicine 1983; 12: 8-12
Expires October 2003

The study

Unblinded ?concealed randomised trial with intention-to-treat
Setting: out-of-hospital, USA

136 patients (aged mean 67 years, 73% male) In cardiac arrest of apparent cardiac aetiology, and not coming out of arrest after specific therapy protocols (refractory). The protocols were defibrillation twice followed by bicarbonate and epinephrine and defibrillation again; or CPR followed by bicarbonate and epinephrine.
Control Group: (n = 70, 70 analysed): no pneumatic trousers
Experimental Group: (n = 66, 66 analysed): pneumatic trousers inflated to the full pressure of 104 mmHg
Any additional therapy was given at the discretion of the physician controlling the therapy, according to American Heart Association guidelines.
100% followed for ? weeks
Outcome notes:
  • survival : discharge from hospital alive
  • resuscitation : admission from the emergency department to the coronary care unit

The evidence

Outcome Time to outcome CEREERRRR
(95% CI)
ARR
(95% CI)
NNT
(95% CI)
survival unknown 3
(4.29%)
6
(9.09%)
5%
(-4% to 13%)
4.81%
(-3.60% to 13.21%)
21
(NNT = 8 to infinity;
NNH = 28 to infinity)
resuscitation unknown 15
(21.4%)
22
(33.3%)
15%
(-5% to 31%)
11.9%
(-2.99% to 26.80%)
8
(NNT = 4 to infinity;
NNH = 33 to infinity)

Comments

  1. The trial was too small to show any clear difference in survival or resuscitation between the two groups.

Citation

  1. Mahoney BD, and Mirick MJ: Efficacy of pneumatic trousers in refractory prehospital cardiopulmonary arrest. Annals of Emergency Medicine 1983; 12: 8-12
Contributor: Clare Wotton and Musab Hayatli, October 1999
Reviewer:

Clinical Question.
Patient refractory prehospital cardiac arrest
Intervention or Exposure pneumatic trousers
Comparison no pneumatic trousers
Outcome mortality