Hypertension: blood pressure should be reduced immediately if evidence of end-organ damage.

Clinical bottom line (level 5)

  1. If there is evidence of end-organ damage, blood pressure should be reduced immediately, otherwise it should be reduced gradually over several hours.
  2. Lifestyle modifications may help lower blood pressure.
  3. Hypertension awareness, treatment and control rates have increased during the past three decades.
: Archives of Internal Medicine 1997; 157: 2413-2446
Expires December 2003

The study

Case series with ?objective ?blinded outcomes, not adjusted for confounding factors, not validated in an independent set of patients.

Setting: USA

0 patients hypertension



Outcomes studied:

The evidence


  • In hypertensive emergencies, require blood pressure to be reduced immediately to prevent or limit target organ damage. In hypertensive urgencies, it is desirable to reduce blood pressure within a few hours.
  • Hypertension awareness, treatment and control rates have increased during the past three decades.
  • Age-adjusted mortality rates for stroke and CHD declined during this time, but are now leveling.
  • End-stage renal disease and prevalence of heart failure are increasing.
  • Prevention and treatment of hypertension and target organ disease remain important public health issues.
  • A significant proportion of cardiovascular disease occurs in people whose blood pressure is above the optimal level (120/ 80 mmHg) but not so high as to be diagnosed or treated as hypertension.
  • lifestyle modifications:
    • lose weight if overweight
    • limit alcohol intake to no more than 30 ml of ethanol per day, or 15 ml per day for women, and lighter-weight people
    • increase aerobic physical activity (30-45 mins most days of the week)
    • reduce sodium intake to no more than 100 mmol/d
    • maintain adequate intake of dietary potassium (~90 mmol/d), calcium and magnesium
    • stop smoking and reduce intake of saturated fat and cholesterol

Comments

  1. National guidelines for hypertension.
  2. This is a source used for bibliographic reference and 'expert opinion'

Citation

  1. , : The sixth report of the Joint National Committee on prevention, detection, evaluation, and treatment of high blood pressure. Archives of Internal Medicine 1997; 157: 2413-2446
Contributor: Clare Wotton, December 2000
Reviewer: Bob Phillips

Clinical Question.
Patient hypertension
Intervention or Exposure
Outcome prevention, detection, evaluation, treatment